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SAGD: Sex-Associated Gene Database

IDNBDC common database IDs, which should be written in parentheses if there are multiple titles, such as Japanese and English. NBDC02571
Database nameName of the database SAGD
Alternative nameAlternative name of the database Sex-Associated Gene Database
URLURL of the database http://bioinfo.life.hust.edu.cn/SAGD
Database maintenance siteSite maintaining the database College of Life Science and Technology, Huazhong Agricultural University
Country/RegionCountry or region name where the database maintenance site is located China
Database descriptionDatabase descirption Many animal species present sex differences. Sex-associated genes (SAGs), which have female-biased or male-biased expression, have major influences on the remarkable sex differences in important traits such as growth, reproduction, disease resistance and behaviors. However, the SAGs resulting in the vast majority of phenotypic sex differences are still unknown. To provide a useful resource for the functional study of SAGs, we manually curated public RNA-seq datasets with paired female and male biological replicates from the same condition and systematically re-analyzed the datasets using standardized methods. We identified 27,793 female-biased SAGs and 64,043 male-biased SAGs from 2,828 samples of 21 species, including human, chimpanzee, macaque, mouse, rat, cow, horse, chicken, zebrafish, seven fly species and five worm species. All these data were cataloged into SAGD, a user-friendly database of SAGs where users can browse SAGs by gene, species, drug, and dataset. In SAGD, the expression, annotation, targeting drugs, homologs, ontology and related RNA-seq datasets of SAGs are provided to help researchers to explore their functions and potential applications in agriculture and human health.
Organism(s) coveredNCBI Taxonomy names and IDs covered by the database Bos taurus (9913), Caenorhabditis (6237), Danio rerio (7955), Drosophila (7215), Equus caballus (9796), Gallus gallus (9031), Homo sapiens (9606), Macaca mulatta (9544), Mus musculus (10090), Pan troglodytes (9598), Pristionchus pacificus (54126), Rattus norvegicus (10116)
Tag - TargetTag to indicate targets for this database such as genome and protein
Genome/Gene
cDNA/EST
Genetic variation
Epigenetics
DNA
RNA
Protein
Carbohydrate
Lipid
Metabolite
Chemical compound
Drug
Cell/Organelle
Organism
Health/Disease
Tag - Information typeTag to indicate information types for this database such as sequence and structure
Phenotype
Bioresource
Method
Ontology/Terminology/Nomenclature
Environment
Sequence
3D structure
Chemical structure
Expression
Localization
Geographic Distribution
Interaction/Pathway
Taxonomy
Classification
Image/Movie
Bibliography/Documents
Portal
Repository
Reference(s) - PubMed ID/DOIPubMed IDs/DOI for papers related to the database
PubMed ID:30380119
DOI:10.1093/nar/gky1040
Language(s)Languages in which the contents of the database are displayed English
Operational statusOperational status for the database Active
Link(s) to Downloadable dataLinks to downloadable data http://bioinfo.life.hust.edu.cn/SAGD#!/download
Link(s) to MetaData of downloadable dataLinks to metadata of downloadable data
Link(s) to Terms of useLinks to terms of use of downloadable data
Link(s) to "How to use" http://bioinfo.life.hust.edu.cn/SAGD#!/help
Contact information of database http://bioinfo.life.hust.edu.cn/SAGD#!/contact/
Link(s) to API / SPARQL endpoint
Link to LSDB ArchiveLink to LSDB Archive
Link to MEDALS Database listLink to MEDALS Database list
Link to TogoTVLink to TogoTV
Link to FAIRsharingLink to FAIRsharing https://fairsharing.org/FAIRsharing.SFORSe
Similar databasesDatabases that are similar to this database.
Record maintainerRecord maintainer See the corresponding part in the FAIRsharing record
Record sourceOrganization that originally created the record
Date of creation of this recordDate of creation of this English record 2021-06-30
Last update date of this recordLast update date of this English record 2021-06-30
Record license Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license