Database Record

Thumbnail

Proteome-pI : proteome isoelectric point database: Proteome-pI

IDNBDC common database IDs, which should be written in parentheses if there are multiple titles, such as Japanese and English. NBDC02184
Database nameName of the database Proteome-pI : proteome isoelectric point database
Alternative nameAlternative name of the database Proteome-pI
URLURL of the database http://isoelectricpointdb.org/
Database maintenance siteSite maintaining the database Quantitative and Computational Biology Group, Max Planck Institute for Biophysical Chemistry
Country/RegionCountry or region name where the database maintenance site is located Germany, Poland
Database descriptionDatabase descirption Proteome-pI is an online database containing information about predicted isoelectric points for 5,029 proteomes (21 million of sequences) calculated using 18 methods. The isoelectric point, the pH at which a particular molecule carries no net electrical charge, is an important parameter for many analytical biochemistry and proteomics techniques, especially for 2D gel electrophoresis (2D-PAGE), capillary isoelectric focusing, liquid chromatography-mass spectrometry and X-ray protein crystallography. The database allows the retrieval of virtual 2D-PAGE plots and the development of customized fractions of proteome based on isoelectric point and molecular weight. Moreover, Proteome-pI facilitates statistical comparisons of the various prediction methods as well as biological investigation of protein isoelectric point space in all kingdoms of life (http://isoelectricpointdb.org/statistics.html). The database includes various statistics and tools for interactive browsing, searching and sorting. It can be searched and browsed by organism name, average isoelectric point, molecular weight or amino acid frequencies. Proteins with extreme pI values are also available. For individual proteomes, users can retrieve proteins of interest given the method, isoelectric point and molecular weight ranges (this particular feature can be highly useful to limit potential targets in analysis of 2DPAGE gels or before conducting mass spectrometry). Finally, some general statistics (total number of proteins, amino acids, average sequence length, amino acid and di-amino acid frequencies) and datasets corresponding to major protein databases such as UniProtKB/TrEMBL and the NCBI non-redundant (nr) database have also been precalculated.
Organism(s) coveredNCBI Taxonomy names and IDs covered by the database All (1)
Tag - TargetTag to indicate targets for this database such as genome and protein
Genome/Gene
cDNA/EST
Genetic variation
Epigenetics
DNA
RNA
Protein
Carbohydrate
Lipid
Metabolite
Chemical compound
Drug
Cell/Organelle
Organism
Health/Disease
Tag - Information typeTag to indicate information types for this database such as sequence and structure
Phenotype
Bioresource
Method
Ontology/Terminology/Nomenclature
Environment
Sequence
3D structure
Chemical structure
Expression
Localization
Geographic Distribution
Interaction/Pathway
Taxonomy
Classification
Image/Movie
Bibliography/Documents
Portal
Repository
Reference(s) - PubMed ID/DOIPubMed IDs/DOI for papers related to the database
PubMed ID:27789699
DOI:-
Language(s)Languages in which the contents of the database are displayed English
Operational statusOperational status for the database Active
Link(s) to Downloadable dataLinks to downloadable data
Link(s) to MetaData of downloadable dataLinks to metadata of downloadable data
Link(s) to Terms of useLinks to terms of use of downloadable data
Link(s) to "How to use"
Contact information of database
Link(s) to API / SPARQL endpoint
Link to LSDB ArchiveLink to LSDB Archive
Link to MEDALS Database listLink to MEDALS Database list
Link to TogoTVLink to TogoTV
Link to FAIRsharingLink to FAIRsharing https://fairsharing.org/10.25504/FAIRsharing.yxkdpg
Similar databasesDatabases that are similar to this database.
Record maintainerRecord maintainer See the corresponding part in the FAIRsharing record
Record sourceOrganization that originally created the record
Date of creation of this recordDate of creation of this English record 2019-03-28
Last update date of this recordLast update date of this English record 2024-07-28
Record license Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license